Response to novel object in Wistar and wild-type (WWCPS) rats

Łukasz Tanaś , Wojciech Pisula

Abstract

Laboratory rats react to a novel object with a rapid redirection of exploratory behaviour towards thesource of the novelty and a subsequent decline of this neotic preference with repeated object exposure.Studies with wild Rattus norvegicus have shown that a novel object in a familiar cage results in avoidance reactions (neophobia) in those animals, but it is also well established that the wild R. norvegicus show strong aversive reactivity to a variety of high intensity stimuli. In this study we aimed to create low stress conditions enabling the comparison of spontaneous exploratory behaviour directed at a novel object in male (age = 80 days) “wild-type” WWCPS rats (n = 21; fourth generation bred in captivity) and Wistar(n = 24) rats. The study involved repeated placing of individual animals in the experimental chamber for 15 (6 min) trials on consecutive days. On the 11th day the novel object was introduced. Animals were tested in darkness and without human presence. Under these conditions neither WWCPS nor Wistar have shown behavioural signs of high emotional arousal, both lines have shown comparable general levels of experimental cage exploration and the positive new object exploratory reaction was observed only in Wistar rats.
Author Łukasz Tanaś (Wydział Psychologii)
Łukasz Tanaś,,
- Wydział Psychologii
, Wojciech Pisula
Wojciech Pisula,,
-
Journal seriesBehavioural Processes, ISSN 0376-6357, (A 25 pkt)
Issue year2011
Vol86
No2
Pages279-283
Publication size in sheets0.5
Keywords in EnglishNeophobia, Wild-type rats, Exploratory behaviour, Neotic preferences, Novel object
DOIDOI:10.1016/j.beproc.2010.12.018
URL http://www.ncbi.nlm.nih.gov/pubmed/21215302
Languageen angielski
File
BEPROC2307-pdf.pdf of 14-09-2015
75.97 KB
Score (nominal)25
Citation count*25 (2020-09-27)
Additional fields
Dorobek Naukowy - Preview URLhttp://dn.swps.edu.pl/Podglad.aspx?WpisID=4291
Dorobek Naukowy - Approve URLhttp://dn.swps.edu.pl/Biuro/ZatwierdzanieWpisu.aspx?WpisID=4291
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* presented citation count is obtained through Internet information analysis and it is close to the number calculated by the Publish or Perish system.
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