Do High Blood Hepcidin Concentrations Contribute to Low Ferritin Levels in Young Tennis Players at the End of Tournament Season?

Ewa Ziemann , Katarzyna Kasprowicz , Kasperska Anna , Zembroń-Łacny Agnieszka , Jędrzej Antosiewicz , Laskowski Radoslaw

Abstract

The purpose of the present study was to verify whether impaired iron metabolism in young athletes is a consequence of an excessive workload during the tournament season. Low levels of ferritin (under 25 μg⋅L-1) have been frequently observed in young tennis players. We considered this finding to be related to the high-intensity workload or to insufficient rest, which both trigger a strong immune response. Groups of male, well-trained young tennis players (16 ± 0.9 years old, average of 10-year training experience) and a control peer group participated in this study. The research consisted of two examination sessions (March and September 2010). Blood samples were collected to determine haematological and immunological parameters. Additionally, body composition and physical capacity were assessed. In both periods of the study, the trained groups were characterised by low levels of ferritin, but also elevated levels of proinflammatory cytokine IL-1β. Moreover, an inverse correlation between IL-1β and blood ferritin was observed. Additionally, an increased concentration of the iron homeostasis regulator hepcidin was found in blood samples (mean 71 ng⋅ml-1; range from 48 to 100 ng⋅ml-1). We concluded that the pro-inflammatory cytokine IL-1β, most likely induced by an extensive workload during the tournament season, was responsible for the low level of ferritin in young, professional athletes.
Author Ewa Ziemann (USSH)
Ewa Ziemann,,
- SWPS University of Social Sciences and Humanities
, Katarzyna Kasprowicz (USSH)
Katarzyna Kasprowicz,,
- SWPS University of Social Sciences and Humanities
, Kasperska Anna
Kasperska Anna,,
-
, Zembroń-Łacny Agnieszka
Zembroń-Łacny Agnieszka,,
-
, Jędrzej Antosiewicz (Wydział Psychologii)
Jędrzej Antosiewicz,,
- Wydział Psychologii
, Laskowski Radoslaw
Laskowski Radoslaw,,
-
Journal seriesJournal of Sports Science and Medicine, ISSN 1303-2968, (A 20 pkt)
Issue year2013
Vol12
Pages249-258
Publication size in sheets0.5
Keywords in EnglishPro-inflammatory cytokine, overreaching, hepcidin
ASJC Classification3612 Physical Therapy, Sports Therapy and Rehabilitation; 2732 Orthopedics and Sports Medicine
URL http://www.jssm.org/abstresearcha.php?id=jssm-12-249.xml
Languageen angielski
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Ziemann-2013-Do-High-Blood-Hepcidin-Concentrations-Contribute-to-Low-Ferritin-Levels-in.pdf of 14-09-2015
351.36 KB
Score (nominal)20
Publication indicators Scopus SNIP (Source Normalised Impact per Paper): 2014 = 1.062; WoS Impact Factor: 2013 = 0.898 (2) - 2013=1.339 (5)
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Dorobek Naukowy - Preview URLhttp://dn.swps.edu.pl/Podglad.aspx?WpisID=13747
Dorobek Naukowy - Approve URLhttp://dn.swps.edu.pl/Biuro/ZatwierdzanieWpisu.aspx?WpisID=13747
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* presented citation count is obtained through Internet information analysis and it is close to the number calculated by the Publish or Perish system.
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