Neural correlates of own name and own face detection in Autism Spectrum Disorder

Hanna B. Cygan , Paweł Tacikowski , Paweł Ostaszewski , Izabela Chojnicka , Anna Nowicka

Abstract

Autism spectrum disorder (ASD) is a heterogeneous neurodevelopmental condition clinically characterized by social interaction and communication difficulties. To date, the majority of research efforts have focused on brain mechanisms underlying the deficits in interpersonal social cognition associated with ASD. Recent empirical and theoretical work has begun to reveal evidence for a reduced or even absent self-preference effect in patients with ASD. One may hypothesize that this is related to the impaired attentional processing of self-referential stimuli. The aim of our study was to test this hypothesis. We investigated the neural correlates of face and name detection in ASD. Four categories of face/name stimuli were used: own, close-other, famous, and unknown. Event-related potentials were recorded from 62 electrodes in 23 subjects with ASD and 23 matched control subjects. P100, N170, and P300 components were analyzed. The control group clearly showed a significant self-preference effect: higher P300 amplitude to the presentation of own face and own name than to the close-other, famous, and unknown categories, indicating preferential attentional engagement in processing of self-related information. In contrast, detection of both own and close-other's face and name in the ASD group was associated with enhanced P300, suggesting similar attention allocation for self and close-other related information. These findings suggest that attention allocation in the ASD group is modulated by the personal significance factor, and that the self-preference effect is absent if self is compared to close-other. These effects are similar for physical and non-physical aspects of the autistic self. In addition, lateralization of face and name processing is attenuated in ASD, suggesting atypical brain organization.
Author Hanna B. Cygan
Hanna B. Cygan,,
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, Paweł Tacikowski
Paweł Tacikowski,,
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, Paweł Ostaszewski (Wydział Psychologii)
Paweł Ostaszewski,,
- Wydział Psychologii
, Izabela Chojnicka
Izabela Chojnicka,,
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, Anna Nowicka
Anna Nowicka,,
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Journal seriesPlos One, ISSN 1932-6203, (A 35 pkt)
Issue year2014
Vol9(1)
Noe86020
Pages1-13
Publication size in sheets4301
ASJC Classification1100 General Agricultural and Biological Sciences; 1300 General Biochemistry, Genetics and Molecular Biology; 2700 General Medicine
DOIDOI:10.1371/journal.pone.0086020
URL http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0086020
Languageen angielski
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cygan-tacikowski-ostaszewski-chojnicka-nowicka-plos-one-2014.pdf of 14-09-2015
95.31 KB
Score (nominal)40
Publication indicators Scopus SNIP (Source Normalised Impact per Paper): 2014 = 1.148; WoS Impact Factor: 2014 = 3.234 (2) - 2014=3.702 (5)
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Dorobek Naukowy - Preview URLhttp://dn.swps.edu.pl/Podglad.aspx?WpisID=14121
Dorobek Naukowy - Approve URLhttp://dn.swps.edu.pl/Biuro/ZatwierdzanieWpisu.aspx?WpisID=14121
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* presented citation count is obtained through Internet information analysis and it is close to the number calculated by the Publish or Perish system.
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