Anxiety, anxiety sensitivity and depression in sarcoidosis

Paweł Holas , Izabela Krejtz , Tomasz Urbankowski , Artur Skowyra , Anna Ludwiniak , Joanna Domagała-Kulawik


Background. Sarcoidosis is a chronic systemic granulomatous disease of unknown etiology. Previ-ous studies demonstrated that patients with sarcoidosis had high rates of depression and anxiety, and high magnitude of stressful life events. To date, however, studies have not examined the anxi-ety sensitivity in sarcoid patients and the relationship between psychopathology and symptomse-verity of sarcoidosis.The aims of this study were to evaluate prevalence of depression and anxiety in sarcoid patients, to assess their relationship with the disease symptom severity, and to investigate the relationship between sarcoidosis and anxiety sensitivity. Methods:Thirty three sarcoid patients and thirty three control subjects completed the following:Hospital Anxiety and Depression Scale, Anxiety Sensitivity Index-3. Results: The prevalence of depression (29%) and anxiety (31%) was high among patients and comparable to results from other research groups. Anxiety was significantly correlated with symptom severity and was the main covariate of physical symptoms reported by sarcoid patients. Patients exhibited an increase of their total anxiety sensitivity index and had an increased number of physical concerns.Conclusions: These data confirmed earlier reports that anxiety and depression are common in patients with sarcoidosis and expanded on the previous results by showing that patients exhibited increased anxiety sensitivity and a fear of physical sensations. These results, together with the findings that anxiety was associated with sarcoidosis symptom severity, suggest that targeting anxiety and the physical health concerns may be important in the diagnosis and management of this disease.
Author Paweł Holas
Paweł Holas,,
, Izabela Krejtz (Wydział Psychologii)
Izabela Krejtz,,
- Wydział Psychologii
, Tomasz Urbankowski
Tomasz Urbankowski,,
, Artur Skowyra
Artur Skowyra,,
, Anna Ludwiniak
Anna Ludwiniak,,
, Joanna Domagała-Kulawik
Joanna Domagała-Kulawik,,
Journal seriesSarcoidosis Vasculitis and Diffuse Lung Diseases, ISSN 1124-0490, (A 20 pkt)
Issue year2013
Publication size in sheets0.5
Keywords in EnglishSarcoidosis, anxiety sensitivity, anxiety
ASJC Classification2740 Pulmonary and Respiratory Medicine; 2700 General Medicine; 2723 Immunology and Allergy; 2724 Internal Medicine
Languageen angielski
06-Holas.pdf of 14-09-2015
93.11 KB
Score (nominal)20
Publication indicators Scopus SNIP (Source Normalised Impact per Paper): 2013 = 1.069; WoS Impact Factor: 2013 = 1.744 (2) - 2013=1.95 (5)
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