Application of directed transfer function and network formalism for assessment of functional connectivity in working memory task

Katarzyna Blinowska , Maciej Kamiński , Aneta Brzezicka , Jan Kacper Kamiński

Abstract

The dynamic pattern of functional connectivity during a working memory task was investigated by means of the short-time directed transfer function. A clear-cut picture of transmissions was observed with the main centres of propagation located in the frontal and parietal regions, in agreement with imaging studies and neurophysiological hypotheses concerning the mechanisms of working memory. The study of the time evolution revealed that most of the time short-range interactions prevailed, whereas the communication between the main centres of activity occurred more sparsely and changed dynamically in time. The patterns of connectivity were quantified by means of a network formalism based on assortative mixing—an approach novel in the field of brain networks study. By means of application of the above method, we have demonstrated the existence of a modular structure of brain networks. The strength of interaction inside the modules was higher than between modules. The obtained results are compatible with theories concerning metabolic energy saving and efficient wiring in the brain, which showed that preferred organization includes modular structure with dense connectivity inside the modules and more sparse connections between the modules.
Author Katarzyna Blinowska
Katarzyna Blinowska,,
-
, Maciej Kamiński
Maciej Kamiński,,
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, Aneta Brzezicka (Wydział Psychologii)
Aneta Brzezicka,,
- Wydział Psychologii
, Jan Kacper Kamiński
Jan Kacper Kamiński,,
-
Journal seriesPhilosophical Transactions of the Royal Society A-Mathematical Physical and Engineering Sciences, ISSN 1364-503X, (A 35 pkt)
Issue year2013
Vol371
No1997
Pages1-16
Publication size in sheets0.75
Keywords in Englishfunctional connectivity, short-time directed transfer function, working memory task, weighted directed networks, community structure of networks
ASJC Classification3100 General Physics and Astronomy; 2200 General Engineering; 2600 General Mathematics
DOIDOI:10.1098/rsta.2011.0614
URL http://dx.doi.org/10.1098/rsta.2011.0614
Languageen angielski
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Blinowska-Kaminski-Brzezicka-Kaminski.pdf of 14-09-2015
1.46 MB
Score (nominal)40
Publication indicators Scopus SNIP (Source Normalised Impact per Paper): 2014 = 1.256; WoS Impact Factor: 2013 = 2.864 (2) - 2013=3.13 (5)
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Dorobek Naukowy - Preview URLhttp://dn.swps.edu.pl/Podglad.aspx?WpisID=16899
Dorobek Naukowy - Approve URLhttp://dn.swps.edu.pl/Biuro/ZatwierdzanieWpisu.aspx?WpisID=16899
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* presented citation count is obtained through Internet information analysis and it is close to the number calculated by the Publish or Perish system.
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