Effects of post-weaning social isolation and environmental enrichment on exploratory behavior and anxiety in Wistar rats

Łukasz Tanaś , Paweł Ostaszewski , Anna Iwan

Abstract

Adverse early experience is generally regarded as a risk factor for both externalizing and internalizing behavioral disorders in humans. It can be modeled in rats by a post-weaning social isolation procedure. Effects of social isolation might possibly be ameliorated by environmental enrichment. In the current study, 24 male Wistar rats were divided post-weaning into four rearing conditions: control, environmental enrichment (EE), social isolation (SI) and a combination of the two experimental conditions; (EE+SI). Two observations of the effects of rearing conditions on the rate of social and object interactions were conducted during the juvenile and post-pubertal stages of development. The SI condition led to a marked increase of social interactions during the juvenile phase, but did not affect object interactions. The EE condition increased the level of social interactions during both the juvenile and post-pubertal measurements. The effects of early rearing conditions on adult exploratory behavior were less clear, with a significant difference between the groups obtained in one of three behavioral tests. Results suggest a general robustness in the development of adult exploratory behavior and anxiety when rats were exposed to early social isolation and provided brief opportunities for social play during the juvenile period. Further studies, aimed at distinguishing play-related protective factors serving against long-term adverse effects of juvenile social isolation, are suggested.
Author Łukasz Tanaś (Wydział Psychologii)
Łukasz Tanaś,,
- Wydział Psychologii
, Paweł Ostaszewski (Wydział Psychologii)
Paweł Ostaszewski,,
- Wydział Psychologii
, Anna Iwan
Anna Iwan,,
-
Journal seriesActa Neurobiologiae Experimentalis, ISSN 0065-1400, (A 20 pkt)
Issue year2015
Vol75
No1
Pages72-97
Publication size in sheets1.25
Keywords in Englishanxiety, play-fighting, exploratory behavior, social isolation, environmental enrichment, rats
ASJC Classification2700 General Medicine; 2800 General Neuroscience
URL http://www.ane.pl/pdf/7506.pdf
Languageen angielski
File
7506.pdf of 14-09-2015
145.11 KB
ANE-2015-rats-play.pdf of 14-09-2015
544.16 KB
Additional file
BROWN_IR-ADV5255_16_0107_001-17.pdf 37.66 KB
BROWN_IR-ADV5255_16_0107_001-55.pdf 21.85 KB
Score (nominal)20
Publication indicators Scopus SNIP (Source Normalised Impact per Paper): 2015 = 0.805; WoS Impact Factor: 2015 = 1.708 (2) - 2015=1.879 (5)
Citation count*19 (2020-10-21)
Additional fields
Dorobek Naukowy - Preview URLhttp://dn.swps.edu.pl/Podglad.aspx?WpisID=17535
Dorobek Naukowy - Approve URLhttp://dn.swps.edu.pl/Biuro/ZatwierdzanieWpisu.aspx?WpisID=17535
Dorobek Naukowy - Preview URLhttp://dn.swps.edu.pl/Podglad.aspx?WpisID=17538
Dorobek Naukowy - Approve URLhttp://dn.swps.edu.pl/Biuro/ZatwierdzanieWpisu.aspx?WpisID=17538
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* presented citation count is obtained through Internet information analysis and it is close to the number calculated by the Publish or Perish system.
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