Prognostic value of perioperative assessment of plasma cardiac troponin I in patients undergoing liver transplantation

Krzysztof Jankowski , Janusz Trzebicki , Maksymilian Bielecki , Beata Łągiewska , Katarzyna Kurnicka , Magdalena Koczaj-Bremer , Marek Pacholczyk , Piotr Pruszczyk

Abstract

An elevation in plasma cardiac troponins is an indicator of increased perioperative risk in orthopaedic and vascular surgery, however, data on liver transplantation (LTx) are scarce. The aim of the study was to evaluate the prevalence of cardiac troponin I (cTnI) elevation in the perioperative period of LTx, and its potential relationship with 1-year mortality.; Material and Methods: Analysis included 79 patients with liver cirrhosis. During LTx all patients underwent hemodynamic measurements. cTnI level was determined before the operation, 24, 48 and 72 hours afterwards. One-year mortality was assessed.; Results: 12.7% patients died, all during in-hospital period. cTnI level on day 1. was identified as the most promising marker of increased death risk with optimal cut-off value of 0.215 ng/mL (the sensitivity of 60.0%, specificity of 87.0%, positive predictive value of 40.0%, negative predictive value of 93.8%). The most important predictor of cTnI increase was the duration of the LT
Author Krzysztof Jankowski
Krzysztof Jankowski,,
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, Janusz Trzebicki
Janusz Trzebicki,,
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, Maksymilian Bielecki (Wydział Psychologii)
Maksymilian Bielecki,,
- Wydział Psychologii
, Beata Łągiewska
Beata Łągiewska,,
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, Katarzyna Kurnicka
Katarzyna Kurnicka,,
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, Magdalena Koczaj-Bremer
Magdalena Koczaj-Bremer,,
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, Marek Pacholczyk
Marek Pacholczyk,,
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, Piotr Pruszczyk
Piotr Pruszczyk,,
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Journal seriesActa Biochimica Polonica, ISSN 0001-527X, (A 15 pkt)
Issue year2017
Vol64
No2016_1436
Pages1-7
Publication size in sheets0.5
Keywords in Englishcardiac troponin I, liver transplantation, surgery time
ASJC Classification1300 General Biochemistry, Genetics and Molecular Biology
DOIDOI:10.18388/abp.2016_1436
URL http://search.ebscohost.com/login.aspx?direct=true&db=cmedm&AN=28455997&lang=pl&site=ehost-live
Languageen angielski
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2017_Jankowski_troponiny.pdf 337.02 KB
Additional file
Oświadczenie_publ.pdf 473.3 KB
Score (nominal)15
ScoreMinisterial score = 15.0, 15-10-2019, ArticleFromJournal
Publication indicators Scopus SNIP (Source Normalised Impact per Paper): 2016 = 0.563; WoS Impact Factor: 2017 = 1.239 (2) - 2017=1.541 (5)
Citation count*1 (2019-10-14)
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* presented citation count is obtained through Internet information analysis and it is close to the number calculated by the Publish or Perish system.
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